UDTR — Radar mondial des droits de la Nature

“Mother-Microbe-Infant-Microbe” Synchrony– A Mini Review

Identification

Clé publique

radar:r-15eac673637f3cf590ddeb5b42400d4d

Auteurs

Prameela Kannan Kutty

Année déclarée

—

Langue déclarée

en

Type source

ART

Première détection

2026-11-13T08:38:55.315705+00:00

Dernière observation des métadonnées

2026-11-13T08:38:55.315705+00:00

Dernière vérification HTTP

Non effectuée

Institutions déclarées par la source

Department of Paediatrics, Faculty of Medicine and Defence Sciences, National University of Defence, Malaysia.

Résumé documentaire — langue originale

Is breast milk nutrition “alive”, dynamic and impossible to emulate? This question remains important in the context of the emergence of novel diseases and may be answered by comparing it to a few events that happen in nature, with parallels evident in the breast feeding dyad. Edified by nature, and its myriad coexisting species, including the microbes, there seems to be much interplay between species through symbiosis, perhaps, with a lofty purpose. This is compared to the breastfeeding infant’s gut that develops in symbiosis with the microbes that enter it through every feed. Breast milk not only nurtures the infant, but also nourishes the commensal microbes it provides. Milk microbes are influenced by maternal, infant and environmental variables, supporting them differently, parallel to the manner in which microbes and other elements in nature support ecosystems. Reviewing and synthesising information from two different but comparable ecosystems show parallels worthy of appraisal. The lactating mammary gland provides and supports beneficial microbes and microbial environments. Secretory immunoglobulin A (sIgA), the key molecule of mucosal gut immunity, is mutualistic with commensal microbes, capable of mucosal defences, yet preserving equilibrium between pathogen defences and commensal tolerance. Through microbial signals, the nursing mother shares her mucosal immune experiences, commenced in utero, transplacentally and then “translactionally”, to mature infant immunity, concluding an exceptional loop of nurture. Technology allows much appreciation that “immune cross- talk” between mother and infant does occur. In this review, commensal gut microbes in the infant are conceptualised as miniature ecosystems and, breastfeeding, as a vibrant compartment where being “alive” pivots in and around microbial existence and sustenance - a biological setting that, at best, may be emulated but not reproduced.

Identifiants

HAL

hal-05284427

Repères documentaires

Famille documentaire

article

Types déclarés par les sources

ART

Les mentions d’entités ne constituent pas une preuve de reconnaissance juridique. La juridiction étudiée est distincte du pays d’affiliation des auteurs.

Sources

HAL · Document 1

• Document · https://hal.science/hal-05284427v1

Statut documentaire

Pertinence à examiner

Bibliothèque

Cette identité n’est pas encore intégrée à la Bibliothèque juridique.