Testosterone therapy over 60 months improves aging male symptoms scores in all men with adult-onset testosterone deficiency
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- doi:10.1080/13685538.2024.2357548
- Authors
- Karim Sultan Haider · Michael Zitzmann · Pravinath Ramachandran · Carola S. König · Geoffrey Ian Hackett · Ahmad Haider · Farid Saad · Pieter Desnerck · Richard C. Strange · Amar Mann · Sudarshan Ramachandran
- Reported year
- 2024
- Reported language
- en
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- article
- First detected
- 2026-11-09T19:15:44.540841+00:00
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- 2026-11-09T19:15:44.540841+00:00
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Aston University · Birmingham City University · Brunel University of London · Gulf Medical University · Keele University · University Hospital Münster · University Hospitals Birmingham NHS Foundation Trust · University of Cambridge
Documentary abstract — original language
Objective We evaluated change (Δ) in AMSS in men with adult-onset testosterone deficiency (TD) on/not on testosterone undecanoate (TU) by analysing a registry of men with adult-onset TD.Methods Analyses were performed using non-parametric statistics to determine ΔAMSS at 6–12 monthly intervals in men on/not on TU and movement in AMSS. Factors predicting ΔAMSS were established via linear/multiple regression.Results TU was significantly associated with lower AMSS values compared with that at baseline/prior assessment during the initial 42 months treatment; 259 of the 260 men showed improvement. In the 361 men not on TU, AMSS values increased during 60 months of follow-up compared with that at baseline/prior assessment; improvement after 60 months was evident in 1 man, whilst AMSS remained the same or worsened in 213 and 147 men, respectively. In men on TU, baseline AMSS was inversely associated with ΔAMSS (R2 = 0.97), with no other factors reaching significance. Baseline AMSS, age, serum total testosterone (TT), waist circumference (WC), and diastolic blood pressure (BP) were associated with ΔAMSS in men not on TU.Discussion We show that TU was associated with lower AMSS in men with adult-onset TD whilst non-treatment led to increased values. Baseline AMSS values inversely predicted ΔAMSS in both groups.
Identifiers
- OPENALEX
- W4399190478
- DOI
- 10.1080/13685538.2024.2357548
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Cite this reference
Karim Sultan Haider; Michael Zitzmann; Pravinath Ramachandran; Carola S. König; Geoffrey Ian Hackett; Ahmad Haider; Farid Saad; Pieter Desnerck; Richard C. Strange; Amar Mann; Sudarshan Ramachandran. Testosterone therapy over 60 months improves aging male symptoms scores in all men with adult-onset testosterone deficiency. 2024. https://doi.org/10.1080/13685538.2024.2357548
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- APA
- Karim Sultan Haider; Michael Zitzmann; Pravinath Ramachandran; Carola S. König; Geoffrey Ian Hackett; Ahmad Haider; Farid Saad; Pieter Desnerck; Richard C. Strange; Amar Mann; Sudarshan Ramachandran. (2024). Testosterone therapy over 60 months improves aging male symptoms scores in all men with adult-onset testosterone deficiency. https://doi.org/10.1080/13685538.2024.2357548
- Chicago
- Karim Sultan Haider; Michael Zitzmann; Pravinath Ramachandran; Carola S. König; Geoffrey Ian Hackett; Ahmad Haider; Farid Saad; Pieter Desnerck; Richard C. Strange; Amar Mann; Sudarshan Ramachandran. Testosterone therapy over 60 months improves aging male symptoms scores in all men with adult-onset testosterone deficiency. 2024. https://doi.org/10.1080/13685538.2024.2357548
- ISO 690
- Karim Sultan Haider; Michael Zitzmann; Pravinath Ramachandran; Carola S. König; Geoffrey Ian Hackett; Ahmad Haider; Farid Saad; Pieter Desnerck; Richard C. Strange; Amar Mann; Sudarshan Ramachandran. Testosterone therapy over 60 months improves aging male symptoms scores in all men with adult-onset testosterone deficiency. 2024. https://doi.org/10.1080/13685538.2024.2357548
UDTR Global Rights of Nature Legal Library. Testosterone therapy over 60 months improves aging male symptoms scores in all men with adult-onset testosterone deficiency. Documentary record: https://www.declarationuniverselledesdroitsdelarbre.org/global-rights-of-nature-radar/reference/r-d06b1dcd03d56d967e70b1d184bdf1ec/ · Last HTTP verification: not performed
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Version 9423e534dd0ae336 · udtr-reference-1.1.2
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- OpenAlex · source · 2026-11-09T19:15:44.540841+00:00
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- OpenAlex · source · 2026-11-09T19:15:44.540841+00:00
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OpenAlex · source · 2026-11-09T19:15:44.540841+00:00
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998621f703a0d120 · 2026-11-09T19:15:44.540841+00:00
c7386f31cf2647c4 · 2026-11-09T19:15:44.540841+00:00
8ee12bf2e2d896c3 · 2026-11-09T19:15:44.540841+00:00
9423e534dd0ae336 · 2026-11-09T19:15:44.540841+00:00
Research dossiers and documentary relations
University Hospitals Birmingham NHS Foundation Trust
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Discovery source · https://doi.org/10.1080/13685538.2024.2357548
Discovery source · https://openalex.org/W4399190478
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